What symptom is commonly associated with pernicious anemia?

Fatigue is commonly associated with pernicious anemia due to the condition's impact on the body's ability to absorb vitamin B12, which is essential for the production of red blood cells. When vitamin B12 levels are low, red blood cell production is impaired, leading to anemia. This decreased oxygen-carrying capacity of the blood can result in feelings of fatigue, weakness, and lethargy. Anemia signifies that the body is not getting enough oxygen to sustain energy levels, which directly correlates to the experience of fatigue in individuals with pernicious anemia.

Other symptoms of pernicious anemia may include pallor, shortness of breath, and neurological issues, but fatigue is particularly prominent and often serves as an indicator that compels individuals to seek medical attention.