Saunders Gastrointestinal Practice Test

The administration of cimetidine and magnesium hydroxide requires careful scheduling due to their pharmacological interactions. Cimetidine is an H2 receptor antagonist used to reduce gastric acid secretion, while magnesium hydroxide is an antacid that neutralizes stomach acid. When combining these medications, it's crucial to space them out to avoid potential interactions that could reduce the effectiveness of cimetidine.

Administering cimetidine 1 hour prior to magnesium hydroxide allows enough time for cimetidine to exert its action by reducing acidity in the stomach. This timing ensures that when magnesium hydroxide is taken afterward, it can effectively neutralize any remaining acid without interfering with the absorption of cimetidine. Therefore, this scheduling is vital for optimizing the therapeutic effects of both medications in managing gastric ulcers.

Drinking water between the medications can be helpful for swallowing pills but is not specifically aimed at the interactions between these medications. Administering both at the same time or collaborating with the healthcare provider for a dual regimen may not address the specific timing recommended for optimal results.